Synthetic Phage Genomics
Developing bottom-up approaches to reconstruct, modularise and systematically engineer bacteriophage genomes, with a focus on Pseudomonas phages and the design rules that govern genome compatibility.
Build. Deliver.
Control.
Our research develops technologies for constructing complex genomes, moving them into new biological contexts, and controlling what engineered systems do once they arrive.
Controllable & Traceable Phages
Engineering replication control, attribution and biocontainment technologies to support responsible deployment of engineered phages.
Cross-Kingdom Engineering
Building broad-host DNA and capsid-based delivery platforms spanning microbes, plants and cellular compartments.
Synthetic Organelles & Genomes
Constructing and delivering large organelle genomes to expand the engineering space beyond the nucleus.
Sequence is the starting material. Biology is the design space.