Research
outputs.
Peer-reviewed publications and current research outputs spanning synthetic genomics, DNA delivery and engineering biology.
Modular synthetic genomics framework for bottom-up engineering of non-model bacteriophage
Cochrane RR, Harrison C, Czernuszka M, Tzokas T, Chen Z, Sunderhauf D, Basit A, Igler C, Wright RCT, Hoffmann S, Brockhurst MA & Cai Y · In preparation
BRIDGE: A broad-host platform for interkingdom DNA delivery enabling the genetic domestication of phylogenetically diverse yeasts
Swidah R, Cochrane RR, Valle F & Delneri D · Nucleic Acids Research · Submitted
The convergence of AI-driven engineering biology and emerging technologies advancing globally networked autonomous biofoundries
Cochrane RR, dos Santos LV & Cai Y · Current Opinion in Biotechnology 99: 103503 · DOI: 10.1016/j.copbio.2026.103503
Engineering conjugative plasmids for inducible horizontal DNA transfer
Jaafar T, Carvalhais E, Shrestha A, Cochrane RR, Meaney JS, Brumwell SL, Hamadache S, Nasrollhi V & Karas BJ · Canadian Journal of Microbiology 71: 1–9 · DOI: 10.1139/cjm-2024-0241
Design and assembly of the 117-kb Phaeodactylum tricornutum chloroplast genome
Walker EJL, Pampuch M, Chang N, Cochrane RR & Karas BJ · Plant Physiology 194(4): 2217–2228 · DOI: 10.1093/plphys/kiad670
Superior conjugative plasmids delivered by bacteria to diverse fungi
Cochrane RR, Shrestha A, Severo de Almeida MM, Agyare-Tabbi M, Brumwell SL, Hamadache S, Meaney JS, Nucifora DP, Say HH, Sharma J, Soltysiak MPM, Tong C, Van Belois K, Walker EJL, Lachance M-A, Gloor GB, Edgell DR, Shapiro RS & Karas BJ · BioDesign Research 9802168 · DOI: 10.34133/2022/9802168
Cloning of Thalassiosira pseudonana’s mitochondrial genome in Saccharomyces cerevisiae and Escherichia coli
Cochrane RR, Brumwell SL, Shrestha A, Giguere DJ, Hamadache S, Gloor GG, Edgell DR & Karas BJ · Biology 9(11): 358 · DOI: 10.3390/biology9110358
Rapid method for generating designer algal mitochondrial genomes
Cochrane RR, Brumwell SL, Soltysiak MPM, Hamadache S, Davis JG, Wang J, Tholl SQ, Jarakirama P, Edgell DR & Karas BJ · Algal Research 50: 102014 · DOI: 10.1016/j.algal.2020.102014
Designer Sinorhizobium meliloti strains and multi-functional vectors enable direct inter-kingdom DNA transfer
Brumwell SL, MacLeod MR, Huang T, Cochrane RR, Meaney RS, Zamani M, Matysiakiewicz O, Dan KN, Janakirama P, Edgell DR, Charles TC, Finan TM & Karas BJ · PLoS ONE 14(7): e0219562 · DOI: 10.1371/journal.pone.0206781